Probably not in Vista and with 2010.  If you were to do a search first, before posting, you would find a thread that advises there was a difficulty with Firefox downloads when MOS was set to on.  This was in a Win 7 machine, and might not apply to you.  Best thing is to try it out.

This is going to be a long learning curve, Calls, and it will be appreciated if you take advantage of the search function to see if you can find some of the info on your own.  We spend a lot of time doing searches to find info for users, that is readily available on the forum.

Spend some time with Norton, look at the intrusion prevention logs, look at Firewall activities, double click on the entries for more information, turn some things on and off, run a couple of scans, and then compile a list of  questions.  Otherwise the forum is only going to have your name on it.