a1420e.dll

get this message constantly and cannot remove the offender

 

Scan type:  Realtime Protection Scan
Event:  Virus Found!
Virus name: Trojan Horse
File:  C:\WINDOWS\system32\a1420e.dll
Location:  C:\WINDOWS\system32
Computer:  IBM-99D43157127
User:  SYSTEM
Action taken:  Clean failed : Quarantine failed : Access denied
Date found: Sunday, March 08, 2009  4:41:20 PM

 

what to do?