Back door trojan msiohpzo quarantined but still causing issues

Hello Everyone

 

Newbie here. Just wondered if anyone can help?

 

Sometime ago NIS quarantined a back door trojan msiohpzo.com stating it was high risk. Quarantine says I don't need to take any further action but when I boot up it takes forever & a message pops up saying could not find c:\users...........\local\temp\msiohpzo.com remove reference from registry. Until I click ok, my laptop will not fully boot up.

 

Ive found file in registry editor, its labelled as load but will not allow me to delete it

 

Ive searched around web trying to find a remedy but so far nothing. Has anyone come across this before?

 

Thank you for taking the time to read