Constant "autoprotect blocked threats" Trojan.Gen.2 , zeroaccess popups

I started getting constant (every 5 min.) popups saying that autoprotect had blocked threats. System now takes inordinate amount of time to boot and I'm getting Google redirects.  Full scan with Norton, along with NPE and remove zero access were unsuccessful. Directed restarts unsuccessful. I'm running XP with SP3. I recieve product through Comcast. Please help!