I was having a browser issue and thought the problem might be related somehow to cookies. I fired up Norton Utilities and rand the cleaner to remove cookies and it said successful. I then went to CCleaner and used their product as a follow-up. When finished I checked Cookies in CCleaner and found that there was still cookies present and all of them ended in safeframe.googlesyndication.com. I then tried to remove them again one by one thru CCleaner but upon a refresh they were back. I know this is a Norton forum so I'm wondering if anyone knows what these cookies are for and why Norton can't get rid of them? I've attached a snapshot of the cookies that can't be deleted.
but upon a refresh they were back
Anytime you refresh a web page your browser is on, it will reload the cookies if they've been removed.
I use Brave instead of Chrome but Brave is Chromium based. What I hate is Google attitude that what's good for Google is good for everyone. Websites put down lots of cookies but they don't set themselves up so they can't be deleted. Another reason to hate Google.
Are you logged into your Google Account in Chrome? That might cause some Google protection for those specific cookies.
Here is some information from Google Support on the safe frame. https://support.google.com/google-ads/thread/1450102?hl=en