DEFRAG OR OPTIMIZE NIS 2010

I haven't defraged my disc C in months and use to do ir routinely, Optimizing seems to clean it up but can you still defrag your drive even if the the analaysis says it's not really needed.Some large type files on there when i view "report. Windows XP Prof/Media Ed. SP2. NIS 2010 Version 17.6..0.32 Thanks in advance........Gorpy 1. P.S New NIS 2010 Version running well for me.