Downloader.misleadapp Virus - Can't remove...

My laptop (running Vista) has been infected with a downloader.misleadapp virus and nothing I've tried to remove it is working.  First, ran liveupdate and tried to scan, but Norton IS09 can't get past "initializing".  Ran update then tried a full scan in safe mode.  Norton scans maybe 1% of my total files then says its complete and finds nothing.  Tried running Malwarebyetes Anti-Malware but it won't load.

 

I certainly appreciate any and all help.  Thanks!