I use both Ghost 14 and Norton 360V3. Each uses a different USB drive and is connected to a different USB Port. They are named GHOST for Ghost14 and LACIE for N360.
The problem is : After running a Ghost incremental backup I cannot remove the Drive. Error is "Generic volume cannot be powered now. TRy later".
After some research I go to Norton 360 "Manage Backup Destination" the Drive GHOST appears there and LACIE is no longer set as destination. This causes N360 next backup to fail. I have to set back LACIE as default.
The only way to remove the Drive GHOST is reboot and remove the USB cable during BIOS phase.
There should be no sharing of files or configuration data between the two products, AT ALL.