Help! need to quarantine or remove infected files

I have Norton 360 through my Comcast internet service and I am getting a Norton pop-up warning that my system is infected and "manual removal' of the infected file is required.  However when I click on the "show me how" buttom, nothing happens.  I finally found the quarantine window and identified several files I wanted to quarantine, but the "removal instructions" button won't work either.  Seems everytime I think I'm about to resolve the issue, I'm blocked from doing it.   Any and all help or suggestions would be greatly appreciated!