How to block ports on particular network interface

I have several network interfaces on my computer and would like to block traffic from all but one port on a particular interface. Norton firewall seems to only allow rules which apply to all network interfaces. Is there a way to set up rules for a given interface, similar to Linux?  I.E. For interfaces "local area 1" and "local area 2" I would like to block all traffic from "local area 2" except for port 443, for example, while letting the normal firewall rules apply to "local area 1".