How to remove globalroot\systemroot\system32\MSIVX?

I’ve been searching the forum but I don’t quite understand what to do.  Every time I open IE i get a message stating globalroot\systemroot… does not work with IE and I should contact the system administrator.  I have tried scanning with Norton’s but it doesn’t seem to do anything, it has scanned for over 6 hours and still going!!  I noticed on another post someone mentioned Avenger, is this a program I can use to remove whatever is on my pc?  Also what is GMER?  HELP!!