N360 vs Windows Defender

Hi

I have bought a new pc (I have upgraded win 8.1 to win 10) and installed N360. N360 have enabled Windows Defender, but obviously not fully correct. Windows Update will not update fx Definition Update for WD - KB2267602 (Definition 1.213.6551.0) - Error 0x80070643.

I can open WD, but most options are blended, and Start button is red, and cliking it gives an error: Service was not started.

I have tried to uninstall N360 - update WD - and then reinstall N360, but that did not solve the problem. Can anyone help me?

Peter