New NIS use. Can I use Returnil/Shadow Defender and Mamutu/Threatfire?

After having used many different products, I finally got tired of constantly having to check to make sure all my different products were in harmony w/each other. So I bought NIS last night.

I would like to know if I can use Returnil/Shadow Defender with NIS without having problems. I prefer Shadow Defender.

Same for Mamutu or Threatfire. I already have a license for Mamutu. If I can use it, are there any settings I should change in NIS?

Lastly, do I need anything like Defensewall with NIS?

I'm still a novice with pcs but can follow instructions pretty well.

Thanks for any help.

jrspie