I'm running 64-bit Office RTM on Win 7 64-bit. NIS 2010 has the settings for Email protection AntiSpam, but the Norton AntiSpam Outlook Plugin won't stay checked in Outlook 2010 File/Options\Add-ins\ Manage COM Add-ins, so I get no NIS AntiSpam in Outlook 2010. 
AntiSpam was my main reason for buying NIS again. We need to know when this will be fixed! Symantec shouldn't use "Office 2010 isn't out yet" as an excuse, as they certainly have had access to all MS apps every step of the way.
[edit: Clarified subject to reflect moved thread.]