NIS 2010: Unable to launch the product after upgrading from 2006

I have recently upgraded from NIS 2006 to NIS 2010 due to having problems running Windows Updates and installing IE8.   There appears to be a problem when running and installing software from various update services.

 

My NIS 2010 System Tray icon is not missing I just cannot start NIS 2010 from System Tray icon, Desktop Shortcut or uistub.exe.

 

I can only run a Full Virus Scan in Safe Mode only.

 

Please help

 

<<Edit: Edited subject as a result of moving the message to a thread of its own>>