Hello!
Running NIS2012 as a Standard User on Windows 7 (x64). Clean install.
So far, File Insight does not pop up once I download a file from the Internet; I've tried this with several downloaded exe's, two from Amazon.com and one from Google (Picasa). Once the file is downloaded, I can do a right-click Insight scan, but it does not take int account the download location (listed as unknown at that point). This functionality works on the other desktops that use Google Chrome.
I know there is an existing known issue with a Diablo download, just wanted to add in that it may be a bit bigger than just Diablo.