Plz plz help I can not get rid of this thing

I seem to have a virus or something that changes the home page of my browsers to searchqu.com/406 no matter how many times I change them back to my preferences. I have NIS 2011 and have run couple  full scans but it doesn't seem to remove this virus-program. Has anyone else had problems with this virus-program and if so how did you get it removed??

 

I had been trying to  get the searchqu.com removed   and dont know how  

 

 

 Please help me  thank you