program keeps asking to run even after I say no - virus?

So on my laptop i keep getting a notification that win(a random number).exe is requesting to run, giving me the usual options to cancel or allow.  I always choose cancel, but a new message pops up almost immediately with a new number.  Publisher is unknown.

 

so for example, it will show up as win2797174368.exe , i choose cancel, and then it comes up as win4956482138.exe asking permission.  This can go on for a half hour before it stops.  I've never had a legitimate program be this intrusive, so I'm wondering if it's a possible virus and what I can do to get it to stop coming up. 

 

I've run full system scans and it hasn't stopped it from happening.