I previously had NIS 2009 installed and all worked fine. Since installing NIS 2010 this morning, I have been getting a runtime error every boot and another notice telling me that SetPoint is not working properly and needs to be reinstalled. I reinstalled it, but it still give me this error. This is the most recent version of Logitech SetPoint, version 4.80. I next installed NIS 2010 on my laptop and encountered the same issue. Has anyone else seen this problem?