Security Question - I.S. Local

I have used Identity Safe for several years now and it has worked fine for me. Recently I have opted to start I.S. when I start Windows, therefore it is essentially on all the time when the computer is not in suspend mode.

 

My question is, if  Identity Safe is left on all the time, can it be accessed by an intruder should they manage to get by my wireless router (firewall) and Norton Internet Security software? Note, I am not concerned with access to my passwords etc, from family members that may use this computer?