Setting up a new computer

I use Windows 10, Norton Antiviris. and Malwarebytes Premium.   I just bought a new computer and wondered if there is a recommended order for installing them. After the initial set up of Windows 10, should I install Norton and Malwarebytes before doing the windows updates , or should I check for and download windows updates first (without Norton Antiviris and Malwarebytes installed and running?)  I ask because now days it takes a couple of hours or more for all the windows updates needed for a new computer. Is that safe without an antivirus program? Or does it not really matter? Thanks for any recommendations.