Should I be running Windows Defender with Norton Security Suite from Comcast?

I see posts here about NOT running Defender w/NIS, in fact I have one PC running NIS 2011 & I believe Defender & NIS 2011 were in conflict & clobbered my PC pretty good.  NIS 2011 does have anti-spyware.  Guess I won't be running Defender on that PC again.

Have two other PC's running Norton Security Suite from Comcast & I can't tell if it has anti-spyware functions or not. Can anyone answer that?  Should I be running Defender along with the Comcast version of Norton?

Didn't think it was possible to run too much anti-spyware?

regards