temp file ~dff7e7.tmp

I have just started seeing a new .tmp file in my %temp% directory that I cannot delete. The latest is ~dff7e7.tmp. It changes each time I start IE. If I shut down and restart computer the same .tmp file is there but when I again open IE a new tmp is created that cannot be deleted but the old .tmp can be deleted. NIS & NPE do not detect any issue and I have also tried Norton Insight network scan function but  it says scan error "unable to open this file make sure the file exist". McAffae indicate this file is a Trojan. Any suggestions?