Trojan.Agent/Gen-UsrMgr Issue

 Today when I did a scan using SUPERAntiSpyware, it showed two files and listed them as critical..  They were both Trojan.agent/gen-UsrMgr and the files were listed as C:\users\(Username)\appdata\local\temp\PYL11B0.tmp.exe and C:\users\(Username)\appdata\local\temp\PYL5BB.tmp.exe.  NIS2012 did not pick up on them and and after putting them in quarantine and rebooting, per SUPERAntiSpyware, neither program show any alerts.  When I checked the folders, the PYL11B0 file was still there.  A few of the files in the PLY11B0 folder are Python23.dll and mail.PYO?  Any information on what these are and why they should have showed up as critical?