UltraDefragger System Crash

I am unable to access any programs - but am now running a full scan. Norton is showing "UltraDefragger  Terminate Process Required  Count 18   Filename hpoqblgcunj.exe" AND "Trojan.Gen.2   Action Quaranteed  Count 2   APQ1AF8.tmp

 

Screen shows many "Failed to save all componants for the file "\\System32\\......."This file is corrupted"

Screen also shows message box "File indexation process failed" (Malware PC Fixit message??)

 

Help, please