WIN 32 Spyware Adware

A couple of weeks ago it was very obvious that I have some type of virus on my system as there is something always running in the backround and I have seen this before.  I have ran several full system scans and it shows nothing.  I ran a scan with Windows defender and it showed three problems   Win 32/Winad Client, Win 32 /Windupdates.A and Win 32/Shop at Home.A    However when I went to delete them, it would not delete stating that some actions couldnt’ be applied to potentially harmful items.  The items may be stored in a read-only location. Delete the files or folders that contain the items.  Only problem is I can’t find them.  Is anyone having this same problem.  This did not start happening until I got on Facebook, but now my system runs constantly and I have tried everything.  Any suggestions?  Thanks!!!