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Please consider this to be entirely unauthoratative, but I don't think the sizes you mention would be considered "large" any longer.
If your computer doesn't have any problem recognizing them, Ghost won't either.
I currently have Norton Ghost 10 and when I try and duplicate drive over 120GB i have errors (do not have the error available to mention) but has to do with partition size of the sorts.
Ghost 14 does not have that type of limitation. I've seen tests upwards of 500 GB. I'm not sure about sizes on the level of Terrabytes though.
By the way, if you are seeing a problem with sector sizing it could be a problem with the partition table and not the size of the drive. You could try running chkdsk /f to see if that resolves things. Otherwise you could post the complete error and we could see what is going on.
Just verified. Ghost 14 supports up to 2 TB partitions for imaging.
thank-you for taking the time to gather the information. I will be purchasing Norton 14 this week ;0]