Help with trojan.zeroaccess.b and trojan.gen.2

I apologize - new here and inadvertantly posted this in Norton 360 a little earler:
This morning norton started repeatedly detecting both  trojan.gen.2 and trojan.zeroaccess.b . I ran Norton's zeroaccess removal tool and the power erasor as instructed on the symantec site. Neither helped. Hoping I can get some additional help here...everything is running extremely slow and "just in time debugging" keeps popping up. Thanks for any help I can get.