How do you remove Bloodhound.PDF.21?

I have tried everything: 

 

1. Disable System Restore ( I have Windows XP)

2. Update the virus definitions

3. Run a full system scan.

 

I have even run a full scan in Safe Mode and I still get the notice of a threat.

Any help someone can provide will be greatly appreciated.

 

I have followed all the directions on the Symantec Website and I have removed this before, but for some reason, I cannot remove this one.  This is so frustrating.