Packed.generic.265 - I cant remove it, need help

My Norton has started coming upi every time I boot up with this Packed.generic.265 virus.  I have folowed the removal instructions, I have gotten the latest updates, then I shout down and reboot in Safe mode.  The I run the full system scan and it comes back with nothing found.  However when I reboot in normal mode the virus is there again.  What am I doing wrong and if nothing, what else can I do?

 

Thanks for the help!