UST GOT ''ERROR 3048,3 -solveds isn't help me!

NIS VER 21.0.1.3    Win 8 

 

Hi -tried reading 'solveds' for my problem but i don't seem to understand 'solutions' ...just got pop up error 3048,3 stating that 'auto-fix' isn't fixing problem ...directed to NIS download page & downloaded 20131003-002-v51 32.exe as instructed...

 

should i do this ?    many thanks  Edythe... (also any gymnastics i should do i e. virus scan, etc. etc.