Just for my edification, and after keeping up with lot of posts on the board I'm not sure I understand what would be considered "advanced" versus I guess basic tools for malware detection and solutions. I fully grasp the concept of "leave it alone and seek expert help." My way of thinking (which may be flawed), running Malwarebytes as a secondary on-demand scanner, AdwCleaner, and running maintenance/tweaking tools like Piriform CCleaner would be considered basic tools. Combofix I'm sure is an advanced tool, and from seeing others use it without expert guidance, it's obviously a recipe for disaster in the hands of the untrained.
It would be helpful to know what tools the experts here consider to be "advanced."
I would consider as safe tools such programs as what is usually recommended in the Forum. In my opinion, they would be the free versionsof Malwarebytes, the free version of SuperAntiSpyware and possibly some parts of CCleaner. I would stay away from any tools that would touch the registry such as registry cleaners. If you take a look around the malware removal sites, any of the tools that they use are primarily advanced tools. Also in this Forum, any tools that Quads would tell some one to use would be considered as advanced tools. Even Hi Jack This in my opinion is an advance tool since you have to know what can be safely removed. A safe tool also has to have a function where you could reverse the operation that it has performed safely although many advaned tools now have that ability also.
You are welcome. If you don't mind, would you please mark the post which answers your question so that if others have a similar question, they will be able to find the solution quickly? Thanks in advance.